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华大时空组学技术Stereo-seq已被成功应用到器官发生、胚胎发育、生命演化、脑科学、肿瘤等多个不同领域,证明了其普适性。未来,时空组学有望应用到生命科学与临床研究的各个领域,尤其疾病研究领域,最终为人类健康带来极大的改善。目前,已有140余篇Stereo-seq及其应用成果发表在CellNatureScience等国际顶级学术期刊。

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141条搜索结果:
Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids

2025-05-16 DOI:10.4240/wjgs.v17.i4.103494

Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids

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期刊·World J Gastrointest Surg 物种·大鼠 样本类型·肛肠
Dev. Cell | Stereo-seq助力构建羊膜类跨物种单细胞图谱,解密3.2亿年大脑演化之谜

2025-05-15 DOI:0.1016/j.devcel.2025.04.014

Dev. Cell | Stereo-seq助力构建羊膜类跨物种单细胞图谱,解密3.2亿年大脑演化之谜

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期刊·Developmental Cell 物种·爬行动物、鸟类和哺乳类等 样本类型·大脑
Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan

2025-04-29 DOI:10.1038/s41592-025-02658-7

Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan

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期刊·Nature Methods 物种·小鼠 样本类型·全脑
Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques

2025-04-28 DOI:10.1038/s44161-025-00639-9

Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques

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期刊·Nature Cardiovascular Research 物种·小鼠及人 样本类型·淋巴器官
Nature子刊 | 首次揭示人类颈动脉斑块中三级淋巴器官!Stereo-seq新突破

2025-04-28 DOI:10.1038/s44161-025-00639-9

Nature子刊 | 首次揭示人类颈动脉斑块中三级淋巴器官!Stereo-seq新突破

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期刊·Nature cardiovascular research 物种·人 样本类型·颈动脉粥样硬化斑块中三级淋巴器官
Single-cell multiome reveals root hair-specific responses to salt stress

2025-04-23 DOI:10.1111/nph.70160

Single-cell multiome reveals root hair-specific responses to salt stress

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期刊·New Phytologist 物种·无头大白菜 样本类型·根尖
Dissecting multilayer cell-cell communications with signaling feedback loops from spatial transcriptomics data

2025-04-22 DOI:10.1101/gr.279857.124

Dissecting multilayer cell-cell communications with signaling feedback loops from spatial transcriptomics data

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期刊·Genome Res 物种·人 样本类型·新冠肺炎感染的肺组织
Nat. Commun | 多样本时空组学数据联合分析工具重磅发布

2025-04-21 DOI: 10.1038/s41467-025-58079-9

Nat. Commun | 多样本时空组学数据联合分析工具重磅发布

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期刊·Nature Communications
Nat. Commun | 首个斑马鱼心脏再生全过程高分辨率时空图谱!Stereo-seq助力揭示心脏再生核心事件

2025-04-19 DOI:10.1038/s41467-025-59070-0

Nat. Commun | 首个斑马鱼心脏再生全过程高分辨率时空图谱!Stereo-seq助力揭示心脏再生核心事件

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期刊·Nature Communications 物种·斑马鱼 样本类型·心脏
Fast analysis of Spatial Transcriptomics (FaST): an ultra lightweight and fast pipeline for the analysis of high resolution spatial transcriptomics

2025-04-17 DOI:10.1093/nargab/lqaf044

Fast analysis of Spatial Transcriptomics (FaST): an ultra lightweight and fast pipeline for the analysis of high resolution spatial transcriptomics

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期刊·NAR Genomics and Bioinformatics